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The primary support camefrom the ARISTOTLE trial (31), in which 18,201patients with AF and a mean CHADS score of 2.1were randomized to receive apixaban 5 mg twicedaily or adjusted-dose warfarin. Recentdata suggest that 2 weeks of initial IV regimen, followed by oral medication for a total ofroughly 6 weeks, may be nearly as effective but safer [26, 49] Recentdata suggest that 2 weeks of initial IV regimen, followed by oral medication for a total ofroughly 6 weeks, may be nearly as effective but safer [26, 49]. A good example of the combination ofattribute and active independent variables in combined experimental–descriptive researchis seen in the study by Rochon, Waters, and Caplan (2000).
This is another form of effect size and is a measure of how much Yincreases as X increases by a specified amount.
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